Consequences of decreased brain serotonin in the pyridoxine-deficient young rat.
نویسندگان
چکیده
The concentrations of serotonin in various brain areas were significantly decreased in the pyridoxine-deficient young rat. There was no change in the concentration of dopamine. Both Bmax and Kd of [3H]serotonin binding to membrane preparations from cerebral cortex were increased in deficiency and were restored to normal upon pyridoxine supplementation. There was no change in [3H]spiroperidol binding to corpus striatal membrane preparations in pyridoxine-deficient rats.
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عنوان ژورنال:
- Progress in neuro-psychopharmacology & biological psychiatry
دوره 7 4-6 شماره
صفحات -
تاریخ انتشار 1983